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Cannabinoids and the Brain (MIT Press), by Linda A. Parker
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The cannabis plant has been used for recreational and medicinal purposes for more than 4,000 years, but the scientific investigation into its effects has only recently yielded useful results. In this book, Linda Parker offers a review of the scientific evidence on the effects of cannabinoids on brain and behavioral functioning, with an emphasis on potential therapeutic uses.
Parker describes the discovery of tetrahydocannbinol (THC), the main psychoactive component of cannabis, and the further discovery of cannabinoid receptors in the brain. She explains that the brain produces chemicals similar to THC, which act on the same receptors as THC, and shows that the endocannabinoid system is involved in all aspects of brain functioning. Parker reports that cannabis contains not only the psychoactive compound THC, but also other compounds of potential therapeutic benefit, and that one of them, cannabidiol (CBD), shows promise for the treatment of pain, anxiety, and epilepsy. Parker reviews the evidence on cannabinoids and anxiety, depression, mood, sleep, schizophrenia, learning and memory, addiction, sex, appetite and obesity, chemotherapy-induced nausea, epilepsy, and such neurodegenerative disorders as multiple sclerosis and Alzheimer's Disease. Each chapter also links the scientific evidence to historical and anecdotal reports of the medicinal use of cannabis. As debate about the medical use of marijuana continues, Parker's balanced and objective review of the fundamental science and potential therapeutic effects of cannabis is especially timely.
- Sales Rank: #224318 in Books
- Published on: 2017-01-13
- Original language: English
- Dimensions: 9.00" h x .50" w x 6.00" l,
- Binding: Hardcover
- 248 pages
Review
Linda Parker is recognized by many of her academic peers as an eminent cannabinoid scientist. The book provides a great read both for those who already possess some, or even a lot of scientific and clinical knowledge about the central effects of cannabis and cannabinoids, and for those who are keen to begin gathering such knowledge.
(Roger Pertwee, Professor, University of Aberdeen, Scotland; cannabinoid pharmacologist; editor of Handbook of Cannabis and Endocannabinoids)This book, written by a superb scientist with decades of experience in the field of endocannabinoids, is an elegant synthesis of a vast literature that has become a hot topic in medicine. It is written in language that is accessible to all and will be engaging for the curious layperson as well as scientists with background and expertise in the cannabinoid field. When medical schools finally catch on that the endocannabinoid system is a critical part of the human immune and pain defense network, this will also serve as a perfect reference text for medical trainees at all levels.
(Mary Lynch, Professor, Department of Anesthesia, Pain Management, and Perioperative Medicine, Dalhousie University)Parker's book is a pleasure to behold -- a treasure trove of knowledge from a much-admired authority in the field of cannabis research. Parker provides a cornucopia of cannabinoid insights for the novice and expert alike: a compact yet richly detailed account of one of the fastest-moving frontiers in science and medicine. Eleven out of ten!
(Iain McGregor, Professor of Psychopharmacology, University of Sydney; Director of Preclinical Research, Lambert Initiative for Cannabinoid Therapeutics) About the Author
Linda A. Parker is Professor in the Psychology and Collaborative Neuroscience Program and Canada Research Chair in Behavioural Neuroscience at the University of Guelph. She was the 2016 recipient of the Lifetime Achievement Award from the International Cannabinoid Research Society and is currently President of the Canadian Consortium for Investigation of Cannabinoids.
Most helpful customer reviews
0 of 0 people found the following review helpful.
Cannabinoids and the Brain is an excellent source for cannabis research
By JJGJR
Cannabinoids and the Brain is an excellent source for cannabis research. The book may be difficult to read for people that don't have a medical or research background. Nevertheless, if you have taken anatomy and physiology I and II in college you should not have much difficulty understanding the terminology.
0 of 0 people found the following review helpful.
Great read !
By Jake M Mendelson
Amazing !
1 of 3 people found the following review helpful.
Not worth the read or the money.
By pamela mccoll
Dear Author - If it was true that cannabinoids were an effective medicine do you not think
that they would have been exploited by the massively wealthy pharmaceutical industry by now ?
In 1985 there was some positive results from scientific study on the chemical THC found in
the cannabis plant (one of 750) but the adverse side effect profile for the use in chemo-therapy
induced nausea and vomiting made it less than desirable. By the 1990s better drugs had been
developed and the pharmaceutical industry moved on - that left THC in the dust. Now in this
decade we see the pharmaceutical industry showing interest in CBD for Dravets - but it is still
in clinical trials for this rare and serious form of epilepsy in childhood and the results are in below
30% for efficacy and again with an adverse side effect profile that includes convulsions.
This book overly in its enthusiastic position on marijuana and its derivatives as medicine and
any book that starts off by saying that a plant has been used for thousands of years is suspect - hemlock,
periwinkle and poppies have been around for thousands of years but luckily we have modern evidence
based scientific study and research so people do not need to revert to primitive medicines with
serious side effects, - wild claims harm far more people than they help. This book is just one more piece of pot propaganda and is not worth the read. If this plant held promise - the pharmaceutical industry would have found it 30 years ago. A waste of time.
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